Working as a bio-statistician across early to late phase oncology clinical trials I come across some contexts where conventional software does not provide the necessary calculations. The calculations themselves can be worked out in a few hours to a day. However there is a need to dig out the appropriate reference, maybe pay for it, read and figure out the results and write code to calculate and check the results – all of which could take a little time and effort. The pages in this section have such calculators. There is a calculator often assessed by users on conditional power calculations, and three other tabs currently contain seven other calculators. Hyperlinks provided here to all the pages and tabs may help the user get to these pages a little easier than through the drop-down menu on smaller devices.
Under the other sample size tab, we have calculators on early phase single sample clinical trials with a survival endpoint, on the Gehan two stage design, on the Cochran-Armitage trend test, and on the sample size for logistic regression. In the trial enrollment tab, there are calculators assessing the influence of large strata or sites in clinical trials and on estimating clinical trial enrollment eligible subgroups in oncology. Computations for observational data include the sample size for matched case-control and cohort studies.
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